La carga viral y los biomarcadores químicos para evaluar la gravedad y el pronóstico en pacientes con SARS-CoV-2.

Francisco Xavier Poveda Paredes; Marcel Alexander Núñez Peralvo; Enrique Alexander Elizalde Enríquez

doi:10.46377/dilemas.v8i1.2454

Francisco Xavier Poveda Paredes Universidad Regional Autónoma de Los Andes
Marcel Alexander Núñez Peralvo Universidad Regional Autónoma de Los Andes
Enrique Alexander Elizalde Enríquez Universidad Regional Autónoma de Los Andes

DOI: https://doi.org/10.46377/dilemas.v8i1.2454

Palabras clave: SARS-Cov-2, Biomarcadores, Carga Viral, Laboratory, Pronóstico COVID-19

Resumen

Este trabajo es una revisiónbibliográfica de artículoscientíficos de alto impacto que se han publicado en los últimos meses sobre el SARS-CoV-2. Se ha reportado que el COVID-19 tiene una alta transmisibilidad y mortalidad, y por ser un virus emergente se han realizado investigaciones sobre sus mecanismos de virulencia y patología; por esta razón, en este estudio se detalla minuciosamente las características moleculares, fisiopatología y la respuesta inmunitaria del paciente frente a la infección, ya que puede ser exacerbada y causar falla multiorgánica desatando el aumento de biomarcadores inflamatorios y de coagulación, que tienen que ser interpretados por el tratante debido a que el aumento exponencial de ferritina, D-Dimero, LDH, Procalcitonina (PCT), se correlacionan como de mal pronóstico del paciente.

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