The viral load and chemical biomarkers to evaluate the severity and prognosis in patients with SARS-CoV-2.

Abstract

This work is a bibliographic review of high impact scientific articles that have been published in previous months on SARS-CoV-2. It has been reported that the COVID-19 has a high transmissibility and mortality;as it an emerging virus, research has been carried out on its mechanisms of virulence and pathology; for this reason,in this study, the molecular characteristics, pathophysiology and the immune response of the patient against infection are detailed since it can be exasperating and cause multiorgan failure, unleashing the increase in inflammatory and coagulation biomarkers, which have to be interpreted by the treating physician because the exponential increase in ferritin, D-Dimer, LDH, Procalcitonin (PCT), is correlated as a poor prognosis of the patient.