Embryonic rhabdomyosarcoma in a pediatric patient
Abstract
It is described the clinical case of a 4 year old male patient who suffered eye trauma due to a blow with the rudder of a motorbike in his right eye, presenting pain as days go by and slight protrusion of the eye, receiving symptomatic treatment with unfavourable evolution; so laboratory tests and radiological studies were performed, Due to the findings of the magnetic resonance imaging, it was decided to take a sample for biopsy, initiating urgent treatment with chemotherapy. The diagnosis is embryonic rhabdomyosarcoma, which presents a good prognosis in 70% of the cases with timely and specific treatment.
References
Arndt C.A, Donaldson SS, Anderson JR, et al. (2001). What constitutes optimal therapy for patients with rhabdomyosarcoma of the female genital tract? Cancer 91 (12): 2454-68.
Bisogno G, Compostella A, Ferrari A, et al. (2012). Rhabdomyosarcoma in adolescents: a report from the AIEOP Soft Tissue Sarcoma Committee. Cancer 118 (3): 821-7.
Casanova M, Meazza C, Favini F, et al. (2009). Rhabdomyosarcoma of theextremities: a focusontumorsarising in thehand and foot. Pediatr Hematol Oncol 26 (5): 321-31, Jul-Aug
Crist W, Gehan EA, Ragab AH, et al. (1995): The Third Intergroup Rhabdomyosarcoma Study. J Clin Oncol 13 (3): 610-30
Diller L, Sexsmith E, Gottlieb A, et al. (1995) Germline p53 mutations are frequently detected in young children with rhabdomyosarcoma. J Clin Invest 95 (4): 1606-11.
Feinberg, A. P., Rainier, S., & DeBaun, M. R. (1995). Genomic imprinting, DNA methylation, and cancer. Monographs-Journal of the National Cancer Institute, (17), 21-26.
Hartley AL, Birch JM, Blair V, et al. (1993). Patterns of cancer in thefamilies of childrenwithsofttissue sarcoma. Cancer august 1, volume 72, No. 3. https://acsjournals.onlinelibrary.wiley.com/doi/pdf/10.1002/1097-0142%2819930801%2972%3A3%3C923%3A%3AAID-CNCR2820720343%3E3.0.CO%3B2-Y
Healthwise, (2019). Tratamiento del rabdomiosarcoma infantil (PDQ®) : Tratamiento - información para profesionales de salud [NCI]: Obtenido de NothShore University HealthSystem: https://www.northshore.org/healthresources/encyclopedia/encyclopedia.aspx?DocumentHwid=ncicdr0000062792&Lang=es-us
Joshi D, Anderson JR, Paidas C, et al. (2004). Age is an independent prognostic factor in rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group. Pediatr Blood Cancer 42 (1): 64-73.
Mafee MF. Órbita (2004): embriología, anatomía y patología. En: Som PM, Curtin HD, eds. Radiología de cabeza y cuello. 4º ed. Madrid: Elsevier; 529-654.
Malempati S, Rodeberg DA, Donaldson SS, et al. (2011). Rhabdomyosarcoma in infants younger than 1 year: a report from the Children's Oncology Group. Cancer 117 (15): 3493-501.
Ognjanovic S, Carozza SE, Chow EJ, et al. (2010). Birth characteristics and the risk of childhood rhabdomyosarcoma based on histological subtype. Br J Cancer 102 (1): 227-31.
Ognjanovic S, Linabery AM, Charbonneau B, et al. (2009): Trends in childhood rhabdomyosarcoma incidence and survival in the United States, 1975-2005. Cancer 115 (18): 4218-26.
Parham DM, Ellison DA (2006). Rhabdomyosarcomas in adults and children: an update. Arch Pathol Lab Med 130 (10): 1454-65, 2006.
Réguerre Y, Martelli H, Rey A, et al. (2012) Local therapy is critical in localised pelvic rhabdomyosarcoma: experience of the International Society of Pediatric Oncology Malignant Mesenchymal Tumor (SIOP-MMT) committee. Eur J Cancer 48 (13): 2020-7.
Sung L, Anderson JR, Donaldson SS, et al. (2004). Late events occurring five years or more after successful therapy for childhood rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group. Eur J Cancer 40 (12): 1878-85.
Trahair T, Andrews L, Cohn RJ. (2007). Recognition of Li Fraumeni syndrome at diagnosis of a locally advanced extremity rhabdomyosarcoma. Pediatr Blood Cancer 48 (3): 345-8.
Van Gaal JC, Van Der Graaf WT, Rikhof B, et al. (2012) The impact of age on outcome of embryonal and alveolar rhabdomyosarcoma patients. A multicenter study. Anticancer Res 32 (10): 4485-97.
Weigel BJ, Breitfeld PP, Hawkins D, et al. (2001). Role of high-dose chemotherapy with hematopoietic stem cell rescue in the treatment of metastatic or recurrent rhabdomyosarcoma. J Pediatr Hematol Oncol 23 (5): 272-6, Jun-Jul.
